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909542-99-0

909542-99-0 Structure

909542-99-0 Structure
IdentificationBack Directory
[Name]

Benfooxythiamine
[CAS]

909542-99-0
[Synonyms]

Benfooxythiamine
Benzenecarbothioicacid,S-[2-[[(1,6-dihydro-2-methyl-6-oxo-5-pyrimidinyl)methyl]formylamino]-1-[2-(phosphonooxy)ethyl]-1-propen-1-yl]ester
[Molecular Formula]

C19H22N3O7PS
[MOL File]

909542-99-0.mol
[Molecular Weight]

467.43
Chemical PropertiesBack Directory
[density ]

1.43±0.1 g/cm3(Predicted)
[pka]

1.84±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

Benfooxythiamine is a transketolase (TKT) inhibitor. Benfooxythiamine inhibits SARS-CoV-2 replication and increases the activity of the glycolysis inhibitor 2DG. Benfooxythiamine has antiviral activit[1].
[References]

[1] Bojkova D, et al. Targeting the Pentose Phosphate Pathway for SARS-CoV-2 Therapy. Metabolites. 2021 Oct 13;11(10):699. DOI:10.3390/metabo11100699
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