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909664-41-1

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909664-41-1 Structure

909664-41-1 Structure
IdentificationBack Directory
[Name]

BPU-11
[CAS]

909664-41-1
[Synonyms]

BPU-11
Biphenyl Urea 11
[Molecular Formula]

C32H31N5O
[MDL Number]

MFCD08561661
[MOL File]

909664-41-1.mol
[Molecular Weight]

501.621
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Description]

BPU-11 is a HCN4 CLP ligand. It acts by modulating channel function and completely abolishing the cAMP-induced shift in V1/2.
[Uses]

BPU-11 is a hyperpolarization-activated cyclic nucleotide-gated (HCN) C-linker pocket (CLP) HCN4 CLP ligand. BPU-11 can be used for the research of congenital immune disease[1].
[References]

[1] Lolicato M, et al. Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness. Nat Chem Biol. 2014 Jun;10(6):457-62. DOI:10.1038/nchembio.1521
Spectrum DetailBack Directory
[Spectrum Detail]

BPU-11(909664-41-1)1HNMR
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