| Identification | Back Directory | [Name]
N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine | [CAS]
912569-84-7 | [Synonyms]
S-methyl DM1
N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine
N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine (>90%) | [Molecular Formula]
C36H50ClN3O10S | [MDL Number]
MFCD34469122 | [MOL File]
912569-84-7.mol | [Molecular Weight]
752.32 |
| Chemical Properties | Back Directory | [Melting point ]
>152°C (dec.) | [Boiling point ]
936.9±65.0 °C(Predicted) | [density ]
1.32±0.1 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
9.82±0.70(Predicted) | [color ]
Off-White to Pale Yellow | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
N2''-Deacetyl-N2''-[3-(methylthio)-1-oxopropyl]-maytansine is an active metabolite of Maytansine (M197940), inhibits in vitro polymerization of tubulin and is used in the treatment of advanced breast cancer. | [IC 50]
Maytansinoids |
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