| Identification | Back Directory | [Name]
Thieno[3,2-d]pyrimidine-3(2H,4H)-butanamide, 1-[2-[(2,6-dimethylphenyl)amino]-2-oxoethyl]-N-[(4-methylphenyl)methyl]-2,4-dioxo- | [CAS]
912799-11-2 | [Synonyms]
SARS-CoV-2 nsp13-IN-5
Thieno[3,2-d]pyrimidine-3(2H,4H)-butanamide, 1-[2-[(2,6-dimethylphenyl)amino]-2-oxoethyl]-N-[(4-methylphenyl)methyl]-2,4-dioxo- | [Molecular Formula]
C28H30N4O4S | [MOL File]
912799-11-2.mol | [Molecular Weight]
518.63 |
| Hazard Information | Back Directory | [Uses]
SARS-CoV-2 nsp13-IN-5 (compound C6) is a potent SARS-CoV-2 nsp13 inhibitor with IC50 values of 50 and 55 μM for ssDNA+ ATPase and ssDNA- ATPase. SARS-CoV-2 nsp13-IN-5 can be used for researching anti-COVID-19[1]. | [References]
[1] Yazdi AK, et al. Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors. ACS Infect Dis. 2022 Jul 13. DOI:10.1021/acsinfecdis.2c00165 |
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