| Identification | Back Directory | [Name]
CARM1 17b | [CAS]
912970-67-3 | [Synonyms]
CARM1 17b
4-[2-(2,6-Dimethoxyphenyl)-7-methyl-1H-benzimidazol-5-yl]-N-methyl-1-piperidineethanamine
2-[4-[2-(2,6-dimethoxyphenyl)-7-methyl-3H-benzimidazol-5-yl]piperidin-1-yl]-N-methylethanamine | [Molecular Formula]
C24H32N4O2 | [MDL Number]
MFCD22683751 | [MOL File]
912970-67-3.mol | [Molecular Weight]
408.536 |
| Hazard Information | Back Directory | [Uses]
CARM1-IN-3 (compound 17b) is a potent and selective co-activator associated arginine methyltransferase (CARM1) inhibitor with IC50 values of 0.07, >25 μM for CARM1 and CARM3, respectively[1]. | [References]
[1] Wan H, et al. Benzo[d]imidazole inhibitors of Coactivator Associated Arginine Methyltransferase 1 (CARM1)--Hit to Lead studies. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5063-6. DOI:10.1016/j.bmcl.2009.07.040 |
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