ChemicalBook--->CAS DataBase List--->913736-92-2

913736-92-2

913736-92-2 Structure

913736-92-2 Structure
IdentificationBack Directory
[Name]

LL-37 GKE
[CAS]

913736-92-2
[Synonyms]

LL-37 GKE
L-Arginine, glycyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-lysyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-arginyl-L-isoleucyl-L-lysyl-L-α-aspartyl-L-phenylalanyl-L-leucyl-L-arginyl-L-asparaginyl-L-leucyl-L-valyl-L-prolyl-
[Molecular Formula]

C119H202N38O28
[MOL File]

913736-92-2.mol
[Molecular Weight]

2613.16
Chemical PropertiesBack Directory
[density ]

1.42±0.1 g/cm3(Predicted)
[Sequence]

Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg
Hazard InformationBack Directory
[Uses]

LL-37 GKE is an active domain of LL-37. LL-37 GKE has antibacterial activity and has potential applications in antibiotics[1][2].
[References]

[1] Sigurdardottir T, et al. In silico identification and biological evaluation of antimicrobial peptides based on human cathelicidin LL-37. Antimicrob Agents Chemother. 2006 Sep;50(9):2983-9. DOI:10.1128/AAC.01583-05
[2] Ringstad L, et al. Effects of single amino acid substitutions on peptide interaction with lipid membranes and bacteria–variants of GKE21, an internal sequence from human LL-37[J]. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2010, 354(1-3): 65-71.
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