| Identification | Back Directory | [Name]
3-AMINO-4-BROMO-1H-INDAZOLE | [CAS]
914311-50-5 | [Synonyms]
4-Bromo-1H-indazol-3-amine
4-bromo-2H-indazol-3-amine
3-AMINO-4-BROMO-1H-INDAZOLE
1H-Indazol-3-aMine, 4-broMo-
4-BroMo-1H-indazol-3-ylaMine | [Molecular Formula]
C7H6BrN3 | [MDL Number]
MFCD09909580 | [MOL File]
914311-50-5.mol | [Molecular Weight]
212.05 |
| Chemical Properties | Back Directory | [Melting point ]
142-144℃ | [Boiling point ]
431.3±25.0 °C(Predicted) | [density ]
1.867±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
Slightly soluble. | [form ]
Crystalline Powder | [pka]
13.68±0.40(Predicted) | [color ]
Off-white to brown to gray |
| Hazard Information | Back Directory | [Uses]
Microwave heating of 2-halobenzaldehydes or 2-haloacetophenones with phenylhydrazines at 160°C for 10 min quantitatively yielded the arylhydrazones, which were further cyclized to give 1-aryl-1H-indazoles via CuI/diamine-catalyzed N-arylation under microwave heating (160°C, 10 min). Good to excellent yields were observed for 2-iodo, 2-bromo, and 2-chloro benzaldehydes or acetophenones. | [Synthesis]
A solution of 2-fluoro-6-bromobenzonitrile (22.0 mmol) and 98% hydrazine hydrate (90.0 mmol) in n-butanol (15 ml) was stirred at reflux for 7 hours. The mixture was cooled to room temperature. The resulting mixture was concentrated under reduced pressure |
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
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| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
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