| Identification | Back Directory | [Name]
Irloxacin | [CAS]
91524-15-1 | [Synonyms]
E-3432
Irloxacin
pirfloxacin
Irloxacin USP/EP/BP
1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1H-pyrrol-1-yl)-3-quinolinecarboxylic acid
1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1H-pyrrol-1-yl)quinoline-3-carboxylic acid | [Molecular Formula]
C16H13FN2O3 | [MDL Number]
MFCD00868661 | [MOL File]
91524-15-1.mol | [Molecular Weight]
300.288 |
| Chemical Properties | Back Directory | [Melting point ]
252-255 °C(Solv: N,N-dimethylformamide (68-12-2)) | [Boiling point ]
495.9±45.0 °C(Predicted) | [density ]
1.36±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:0.0(Max Conc. mg/mL);0.0(Max Conc. mM) | [form ]
Solid | [pka]
-0.07±0.20(Predicted) | [color ]
White to off-white | [CAS DataBase Reference]
91524-15-1 |
| Hazard Information | Back Directory | [Hazard]
Low toxicity by ingestion. | [Uses]
Irloxacin (Pirfloxacin) is a quinolone antibacterial agent. Irloxacin shows greater activity with an acid pH. Irloxacin has a good in vitro antimicrobial spectrum against both gram-positive and gram-negative bacteria. Orally active[1]. | [storage]
Store at -20°C | [References]
[1] Casal M, et al. Preliminary study of the in vitro activity of irloxacin against mycobacteria. Chemotherapy. 1995;41(3):204-207. DOI:10.1159/000239345
[2] Guzmán A, et al. Acute and subchronic toxicity studies of the new quinolone antibacterial agent irloxacin in rodents. Arzneimittelforschung. 1999;49(5):448-456. DOI:10.1055/s-0031-1300441 |
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