| Identification | Back Directory | [Name]
Timolol hemihydrate | [CAS]
91524-16-2 | [Synonyms]
(-) S Timolol
(-)-S-Timolol
Timolol hemihydrate
(S)-timolol hemihydrate | [Molecular Formula]
C26H50N8O7S2 | [MDL Number]
MFCD29920166 | [MOL File]
91524-16-2.mol | [Molecular Weight]
650.855 |
| Hazard Information | Back Directory | [Uses]
Betimol(Sanofi Winthrop). | [Definition]
ChEBI: (S)-timolol hemihydrate is a hydrate, which is the hemihydrate form of the (S)-(-) (more active) enantiomer of timolol. It has a role as an antihypertensive agent, an anti-arrhythmia drug, a beta-adrenergic antagonist and an antiglaucoma drug. It contains a (S)-timolol (anhydrous). | [in vivo]
Timolol (hemihydrate) (5 mg/kg daily for 12-week) has a cardioprotective effect via inhibition of ERS response in diabetic rats[3]. | Animal Model: | Male Wistar rats[3]. | | Dosage: | 5 mg/kg | | Administration: | Timolol (5 mg/kg daily for 12-week) | | Result: | Showed cardioprotective effect. |
| [IC 50]
β adrenergic receptor |
|
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