| Identification | Back Directory | [Name]
Benzoic acid, 2-[(1H-indol-3-ylcarbonyl)amino]-, methyl ester | [CAS]
915315-44-5 | [Synonyms]
cephalandole B
Benzoic acid, 2-[(1H-indol-3-ylcarbonyl)amino]-, methyl ester | [Molecular Formula]
C17H14N2O3 | [MOL File]
915315-44-5.mol | [Molecular Weight]
294.31 |
| Chemical Properties | Back Directory | [Melting point ]
179.5-180 °C(Solv: ethyl ether (60-29-7)) | [Boiling point ]
431.3±25.0 °C(Predicted) | [density ]
1.346±0.06 g/cm3(Predicted) | [pka]
14.26±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
Cephalandole B is an indigo alkaloid that has the activity of inhibiting IL-17A gene expression. Cephalandole B significantly inhibited the activity of IL-17A luciferase reporter gene in Jukat cells, and this inhibitory effect was dose-dependent. Cephalandole B may have important application prospects in inflammation-related research[1]. | [References]
[1] IL-17A inhibitions of indole alkaloids from traditional Chinese medicine Qing Dai |
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