| Identification | Back Directory | [Name]
BMS 767778 | [CAS]
915729-95-2 | [Synonyms]
BMS 767778
BMS767778,BMS 767778
6H-Pyrrolo[3,4-b]pyridine-6-acetamide, 3-(aminomethyl)-4-(2,4-dichlorophenyl)-5,7-dihydro-N,N,2-trimethyl-5-oxo-, (4S)- | [Molecular Formula]
C19H20Cl2N4O2 | [MOL File]
915729-95-2.mol | [Molecular Weight]
407.29 |
| Hazard Information | Back Directory | [Uses]
BMS-767778 is a selective DPP4 inhibitor, with a Ki of 0.9 nM[1]. | [References]
[1] Pratik Devasthale, et al. Optimization of activity, selectivity, and liability profiles in 5-oxopyrrolopyridine DPP4 inhibitors leading to clinical candidate (Sa)-2-(3-(aminomethyl)-4-(2,4-dichlorophenyl)-2-methyl-5-oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)-N,N-dimethylacetamide (BMS-767778). J Med Chem . 2013 Sep 26;56(18):7343-57. DOI:10.1021/jm4008906 |
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