| Identification | Back Directory | [Name]
Ibafloxacine | [CAS]
91618-36-9 | [Synonyms]
R835
S 25930
Ibafloxacine
6,7-Dihydro-9-fluoro-5,8-dimethyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid
9-Fluoro-6,7-dihydro-5,8-dimethyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid
1H,5H-Benzo[ij]quinolizine-2-carboxylic acid, 9-fluoro-6,7-dihydro-5,8-dimethyl-1-oxo- | [Molecular Formula]
C15H14FNO3 | [MDL Number]
MFCD00865094 | [MOL File]
91618-36-9.mol | [Molecular Weight]
275.27 |
| Chemical Properties | Back Directory | [Melting point ]
269-272° | [Boiling point ]
477.5±45.0 °C(Predicted) | [density ]
1.40±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
5.71±0.40(Predicted) |
| Hazard Information | Back Directory | [Uses]
Antibacterial. | [in vivo]
The pharmacokinetic behavior of Ibafloxacin is studied after intravenous administration of a single dose of 15 mg/kg to 6 healthy lactating goats. Plasma concentrations of Ibafloxacin are determined by high-performance liquid chromatography with fluorescence detection. After IV injection Ibafloxacin shows very rapid initial distribution, with a mean half-life of 0.35 h, follows by slower elimination, with a mean half-life of 3.76 h. The elimination half-life of Ibafloxacin after oral administration has been reported to be 3.83 h in dogs and 3.00 h in cats[1]. | [IC 50]
Quinolone |
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