| Identification | Back Directory | [Name]
Silicate(4-?)?, [2,?5-?dioxo-?1-?pyrrolidinyl 6-?[[[3-?[(29H,?31H-?phthalocyanin-?1-?yl-?κN29,?κN30,?κN31,?κN32)?oxy]?propoxy]?carbonyl]?amino]?hexanoato(2-?)?]?bis[N-?[3-?[(hydroxy-?κO)?dimethylsilyl]?propyl]?-?3-?sulfo-?N,?N-?bis(3-?sulfopropyl)?-?1-?pr | [CAS]
916821-46-0 | [Synonyms]
IRDye701Dx
IRDye700DX NHS
IRDye 700DX NHS Ester
photosensitizer DK1232
Silicate(4-?)?, [2,?5-?dioxo-?1-?pyrrolidinyl 6-?[[[3-?[(29H,?31H-?phthalocyanin-?1-?yl-?κN29,?κN30,?κN31,?κN32)?oxy]?propoxy]?carbonyl]?amino]?hexanoato(2-?)?]?bis[N-?[3-?[(hydroxy-?κO)?dimethylsilyl]?propyl]?-?3-?sulfo-?N,?N-?bis(3-?sulfopropyl)?-?1-?pr | [Molecular Formula]
C74H96N12NaO27S6Si3(-3) | [MOL File]
916821-46-0.mol | [Molecular Weight]
1885.25 |
| Hazard Information | Back Directory | [Uses]
IRDye 700DX (IRDye 700DX NHS ester) is a near-infrared (NIR) phthalocyanine dye with extremely high photostability and fluorescence intensity. IRDye 700DX binds to biomolecules. IRDye 700DX has excellent water solubility, large extinction coefficient, high fluorescence quantum yield, and does not aggregate in high ionic strength buffers. IRDye 700DX can be used as a highly flexible photosensitizer[1][2][3]. | [References]
[1] Mitsunaga M, et al. Cancer cell-selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules. Nat Med. 2011 Nov 6;17(12):1685-91. DOI:10.1038/nm.2554
[2] Peng X, et al. Phthalocyanine dye as an extremely photostable and highly fluorescent near-infrared labeling reagent[C]//Optical Molecular Probes for Biomedical Applications. SPIE, 2006, 6097: 113-124.
[3] Tynan CJ, et al. Multicolour single molecule imaging in cells with near infra-red dyes. PLoS One. 2012;7(4):e36265. DOI:10.1371/journal.pone.0036265 |
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