| Identification | Back Directory | [Name]
3'-Deoxy-3'-fluoro-5-methyl-xylo-uridine | [CAS]
917110-29-3 | [Synonyms]
3'-Deoxy-3'-fluoro-5-methyl-xylo-uridine
3’-Deoxy-3’-fluoro-5-methyl-xylo-uridine
2,4(1H,3H)-Pyrimidinedione, 1-(3-deoxy-3-fluoro-β-D-xylofuranosyl)-5-methyl-
1-((2R,3S,4R,5R)-4-Fluoro-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione | [Molecular Formula]
C10H13FN2O5 | [MDL Number]
MFCD30570227 | [MOL File]
917110-29-3.mol | [Molecular Weight]
260.22 |
| Hazard Information | Back Directory | [Uses]
3’-Deoxy-3’-fluoro-5-methyl-xylo-uridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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