| Identification | Back Directory | [Name]
4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester | [CAS]
917392-54-2 | [Synonyms]
NILOTINIB EP IMPURITY G
methyl 4-methyl-3-[[4-(3-pyridyl)pyrimidin-2-yl]amino]benzoate
Methyl 4-Methyl-3-((4-(pyridin-3-yl)pyriMidin-2-yl)aMino)benzoate
4-Methyl-3-(4-pyridin-3-yl-pyriMidin-2-ylaMino)-benzoic acid Methyl ester
4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester
Benzoicacid, 4-Methyl-3-[[4-(3-pyridinyl)-2-pyriMidinyl]aMino]-, Methyl ester
Methyl 4-Methyl-3-((4-(pyridin-3-yl)pyriMidin-2-yl)aMino)benzoate, Methyl 4-Methyl-3-(4-(pyridin-3-yl)pyriMidin-2-ylaMino)benzoate | [Molecular Formula]
C18H16N4O2 | [MDL Number]
MFCD16619370 | [MOL File]
917392-54-2.mol | [Molecular Weight]
320.35 |
| Chemical Properties | Back Directory | [Melting point ]
148 - 150°C | [Boiling point ]
538.6±60.0 °C(Predicted) | [density ]
1.258 | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
Chloroform (Slightly), DMSO (Slightly) | [form ]
Solid | [pka]
2.70±0.12(Predicted) | [color ]
Pale Yellow to Light Beige | [InChI]
InChI=1S/C18H16N4O2/c1-12-5-6-13(17(23)24-2)10-16(12)22-18-20-9-7-15(21-18)14-4-3-8-19-11-14/h3-11H,1-2H3,(H,20,21,22) | [InChIKey]
BECBKQYLJDEVDN-UHFFFAOYSA-N | [SMILES]
C(OC)(=O)C1=CC=C(C)C(NC2=NC=CC(C3=CC=CN=C3)=N2)=C1 |
| Hazard Information | Back Directory | [Uses]
Methyl 4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]benzoate is an intermediate used in the synthesis of 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide (M326838), which is an impurity of Nilotinib (N465300), a possible agent in the treatment of chronic myelogenous leukemia. |
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