| Identification | Back Directory | [Name]
ANP 1-28, HUMAN | [CAS]
91917-63-4 | [Synonyms]
HANF
ANF 1-28, HUMAN
ANP 1-28, HUMAN
ANP HUMAN, 1-28
ANP, ALPHA-, HUMAN
α-ANF(1-28), human
a-ANF(1-28), human
ALFA-ANF(1-28), HUMAN
ALPHA-ANF (1-28), HUMAN
Atriopeptin-28【dog reduced】
[MET(O)12]-ANP (HUMAN, 1-28)
SLRRSSCFGGRMDRIGAQSGLGCNSFRY
ANF 1-28, hANF, Urodilatin
ATRIAL NATRIURETIC PEPTIDE HUMAN
M.W. 3080.47 C127H203N45O39S3
alpha-Atriopeptin (human reduced)
ATRIAL NATRIURETIC FACTOR 1-28, HUMAN
ATRIAL NATRIURETIC PEPTIDE HUMAN, 1-28
ATRIAL NATRIURETIC PEPTIDE 1-28, HUMAN
ALPHA-ATRIAL NATRIURETIC PEPTIDE, HUMAN
Atriopeptin-28 (Canis familiaris reduced)
ATRIAL NATRIURETIC PEPTIDE, ALPHA-, HUMAN
ANP (HUMAN, 1-28) (PORCINE, BOVINE, CANINE)
Atrial natriuretic peptide-28 (human reduced)
Atrial natriuretic peptide-28 (Canis familiaris)
ATRIAL NATRIURETIC FACTOR (1-28) (HUMAN, CANINE)
[MET(O)12]-A-TYPE (ATRIAL) NATRIURETIC PEPTIDE (HUMAN, 1-28)
A-TYPE (ATRIAL) NATRIURETIC PEPTIDE (HUMAN, 1-28) (PORCINE, BOVINE, CANINE)
SER-LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR
SER-LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET(O)-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR
SER-LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR(DISULFIDE BRIDGE:CYS7-CYS23)
REF DUPL: Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr (disulfide bridge Cys7-Cys23)
L-Ser-L-Leu-L-Arg-L-Arg-L-Ser-L-Ser-L-Cys-L-Phe-Gly-Gly-L-Arg-L-Met-L-Asp-L-Arg-L-Ile-Gly-L-Ala-L-Gln-L-Ser-Gly-L-Leu-Gly-L-Cys-L-Asn-L-Ser-L-Phe-L-Arg-L-Tyr-OH
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(4R,10S,16S,19S,22S,28S,31S,34S,37S,40S,49S,52R)-52-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxy-propanoyl]amino]-4-methyl-pentanoyl]amino]-5-guanidino-pentanoyl]amino]-5-guanid | [Molecular Formula]
C127H203N45O39S3 | [MDL Number]
MFCD00076226 | [MOL File]
91917-63-4.mol | [Molecular Weight]
3080.44 |
| Chemical Properties | Back Directory | [density ]
1.54±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C | [form ]
Lyophilized powder | [Water Solubility ]
Soluble to 1 mg/ml in water | [Sequence]
Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr | [InChIKey]
KGZJRXKGJRJKCB-UHFFFAOYSA-N |
| Hazard Information | Back Directory | [Uses]
Atrial natriuretic peptide (ANP) has been used to study its cross reactivity in melanin concentrating hormone (MCH) assay. It has also been used to study its effects in nerve fibres and nerve cell bodies. | [Biochem/physiol Actions]
Atrial natriuretic peptide (ANP) is synthesized in myoendocrine cells of the heart from which it is released into the circulation. It exerts natriuretic, diuretic, and vasodilatory effects through stimulation of guanylate cyclase-linked NPR-A receptors. It plays an important role in blood volume and blood pressure homeostasis. | [in vivo]
ANF-(1-28) (0.5 μg/kg/min) infusion attenuates the rise in plasma creatinine levels by approximately 50% on each day of the study[3]. | [storage]
Store at -20°C |
|
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Sigma-Aldrich
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