| Identification | Back Directory | [Name]
1H-Pyrrolo[2,3-b]pyridine-5-carbonitrile, 4-chloro- | [CAS]
920966-02-5 | [Synonyms]
3-b]pyridine-5-carbonitrile
4-Chloro-5-cyano-7-azaind...
4-Chloro-5-cyano-7-azaindole
6-Fluoro-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde
4-Chloro-1H-Pyrrollo[2,3-b]pyridine-5-carbonitrile
1H-Pyrrolo[2,3-b]pyridine-5-carbonitrile, 4-chloro-
1H-Pyrrolo[2,3-b]pyridine-5-carbonitrile, 4-chloro- ISO 9001：2015 REACH | [Molecular Formula]
C8H4ClN3 | [MDL Number]
MFCD09965877 | [MOL File]
920966-02-5.mol | [Molecular Weight]
177.59 |
| Questions And Answer | Back Directory | [Uses]
4-Chloro-1H-pyrrolo[2,3-B]pyridine-5-carboxynitrile can be used in biological research. The pyrrolopyridine skeleton can be classified into six different structures according to the different combinations of pyrrole and pyridine: pyrrolo[3,2-b]pyridine, pyrrolo[3,4-b]pyridine, and pyrrolo[2,3-b]pyridine. Cyclization of pyrrole and pyridine compounds forms heterocyclic compounds with pyrrolopyridine or similar structural characteristics, all exhibiting potential biological activity. Many new active intermediates subsequently become important raw materials in drug synthesis. Designing and innovatively synthesizing drugs with excellent biological activity and low toxicity is always a research topic of common concern and great interest to organic synthetic and drug research developers. These derivatives exist in alkaloids such as ASP3627, Mappicine, and Vemurafenib, and can be used as LRRK2 inhibitors, MPS1 inhibitors, JAK1 inhibitors, and Met kinase inhibitors. |
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