| Identification | Back Directory | [Name]
2-Amino-6-allylthio-9-(beta-D-ribofuranosyl)-9H-purine | [CAS]
92104-54-6 | [Synonyms]
6-S-Allyl-6-thio-guanosine
2-Amino-6-allylthio-9-(beta-D-ribofuranosyl)-9H-purine
9H-Purine, 6-(allylthio)-2-amino-9-β-D-ribofuranosyl- (7CI)
2-Amino-6-allylthio-9-(beta-D-ribofuranosyl)-9H-purine, 6-S-Allyl-6-thio-guanosine | [Molecular Formula]
C13H17N5O4S | [MDL Number]
MFCD31814018 | [MOL File]
92104-54-6.mol | [Molecular Weight]
339.37 |
| Hazard Information | Back Directory | [Uses]
2-Amino-6-allyl thio-9-(beta-D-ribofuranosyl)-9H-purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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