ChemicalBook--->CAS DataBase List--->921618-45-3

921618-45-3

921618-45-3 Structure

921618-45-3 Structure
IdentificationBack Directory
[Name]

Camidanlumab
[CAS]

921618-45-3
[Synonyms]

Camidanlumab
Research Grade Camidanlumab
Research Grade Camidanlumab(DHB95803)
Chemical PropertiesBack Directory
[form ]

Liquid
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Uses]

Camidanlumab (HuMax-TAC) is a CD25 monoclonal antibody. Camidanlumab targets the cell-surface antigen CD25, which is over-expressed on a variety of hematological tumors and shows limited expression on normal tissues. Camidanlumab can be used for synthesis of antibody agent conjugates (ADCs) to research several diseases including lymphoma and leukemia[1].
[References]

[1] Michael J Flynn, et al. ADCT-301, a Pyrrolobenzodiazepine (PBD) Dimer-Containing Antibody-Drug Conjugate (ADC) Targeting CD25-Expressing Hematological Malignancies. Mol Cancer Ther. 2016 Nov;15(11):2709-2721. DOI:10.1158/1535-7163.MCT-16-0233
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