| Identification | Back Directory | [Name]
NEUROMEDIN N | [CAS]
92169-45-4 | [Synonyms]
KIPYIL
canine)
KIPYIL-NH2
NEUROKININ N
NEUROMEDIN N
Neuromedin N (rat
NEUROMEDIN N (PORCINE)
LYS-ILE-PRO-TYR-ILE-LEU
H-LYS-ILE-PRO-TYR-ILE-LEU-OH
Neuromedin N (swine spinal cord)
L-Lys-L-Ile-L-Pro-L-Tyr-L-Ile-L-Leu-OH
NEUROMEDIN N (RAT, MOUSE, PORCINE, CANINE)
L-Leucine, L-lysyl-L-isoleucyl-L-prolyl-L-tyrosyl-L-isoleucyl-
LYS-ILE-PRO-TYR-ILE-LEU;NEUROMEDIN N (RAT; MOUSE; PORCINE; CANINE)
Neuromedin N,Lys-Ile-Pro-Tyr-Ile-Leu,Neuromedin N (rat, mouse, porcine, canine), BR | [Molecular Formula]
C38H63N7O8 | [MDL Number]
MFCD00076669 | [MOL File]
92169-45-4.mol | [Molecular Weight]
745.95 |
| Chemical Properties | Back Directory | [Boiling point ]
1071.579±65.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.186±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [storage temp. ]
-15°C | [solubility ]
H2O : 50 mg/mL (67.03 mM; Need ultrasonic) | [form ]
Powder | [pka]
3.408±0.10(predicted) | [color ]
White to off-white | [Sequence]
Lys-Ile-Pro-Tyr-Ile-Leu |
| Hazard Information | Back Directory | [Uses]
Neuromedin N is a neurotensin-like peptide. | [Biological Activity]
Neuromedin N is a hexapeptide th at is related to neurotensin. Its precursorproneuromedin Nis expressed in the adrenalsbraingut and also in several cancers. In myoelectric activityit has been reported to act in a similar manner as neurotensin at a lesser degree of potency. Neuromedin N has been shown to increase the chemotaxis capacity of mouse lymphocytes and to modulate function of the hypothalamo-pituitary-adrenocortical axis in rats. Neuromedin N has been proposed to exert its actions via increase in intracellular Ca2+ concentrationalthough this is uncertain. | [IC 50]
D2 Receptor |
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