| Identification | Back Directory | [Name]
Isothiazolo[5,4-b]quinoline-3,4(2H,9H)-dione, 7-[(3R)-3-(1-amino-1-methylethyl)-1-pyrrolidinyl]-9-cyclopropyl-6-fluoro-8-methoxy- | [CAS]
922491-46-1 | [Synonyms]
ACH702
ACH-702
ACH 702
Isothiazolo[5,4-b]quinoline-3,4(2H,9H)-dione, 7-[(3R)-3-(1-amino-1-methylethyl)-1-pyrrolidinyl]-9-cyclopropyl-6-fluoro-8-methoxy- | [Molecular Formula]
C21H25FN4O3S | [MOL File]
922491-46-1.mol | [Molecular Weight]
432.51 |
| Hazard Information | Back Directory | [Uses]
ACH-702 is a potent anti-tubercular agent. ACH-702 also shows broad-spectrum antibacterial activity[1][2]. | [References]
[1] Molina-Torres CA, et al. In vitro activity of a new isothiazoloquinolone, ACH-702, against Mycobacterium tuberculosis and other mycobacteria. Antimicrob Agents Chemother. 2010 May;54(5):2188-90. DOI:10.1128/AAC.01603-09
[2] Pucci MJ, et al. In vitro and in vivo profiles of ACH-702, an isothiazoloquinolone, against bacterial pathogens. Antimicrob Agents Chemother. 2011 Jun;55(6):2860-71. DOI:10.1128/AAC.01666-10 |
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