| Identification | Back Directory | [Name]
Hydroxybupropione | [CAS]
92264-81-8 | [Synonyms]
HYDROXYBUPROPION
HYDROXYBUPROPIONE
Bupropion Impurity 7
(±)-Hydroxybupropion solution
2-HYDROXY-2-(3'-CHLOROPHENYL)-3,5,5-TRIMETHYLMORPHOLINE
1-(3-Chlorophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]-1-propanone
1-(3-CHLOROOPHENYL)-2-[(2-HYDROXY-1,1-DIMETHYLETHYL)AMINO]-1-PROPANONE
1-(3-Chlorophenyl)-2-[(1-hydroxy-2-methylpropan-2-yl)amino]propan-1-one
1-(3-Chloroophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]-1-propanone, 2-Hydroxy-2-(3chlorophenyl)-3,5,5-trimethylmorpholine | [EINECS(EC#)]
200-835-2 | [Molecular Formula]
C13H18ClNO2 | [MDL Number]
MFCD03701187 | [MOL File]
92264-81-8.mol | [Molecular Weight]
255.74 |
| Chemical Properties | Back Directory | [Appearance]
Off-White Solid | [Melting point ]
121-123°C | [Boiling point ]
393.9±32.0 °C(Predicted) | [density ]
1.150±0.06 g/cm3(Predicted) | [Fp ]
2℃ | [storage temp. ]
?20°C | [solubility ]
Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly) | [form ]
Solid | [pka]
15.43±0.10(Predicted) | [color ]
White to Pale Yellow | [Major Application]
clinical testing | [InChI]
1S/C13H18ClNO2/c1-9-13(16,17-8-12(2,3)15-9)10-5-4-6-11(14)7-10/h4-7,9,15-16H,8H2,1-3H3 | [InChIKey]
RCOBKSKAZMVBHT-UHFFFAOYSA-N | [SMILES]
ClC1=CC(C2(O)C(C)NC(C)(C)CO2)=CC=C1 |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White Solid | [Uses]
A metabolite of Bupropion, an antidepressant. The compound exists mainly as cyclic acetal (2-hydroxy-2-(3?chlorophenyl)-355-trimethylmorpholine). See US Pat. # 6342496 | [Definition]
ChEBI: Hydroxybupropion is an aromatic ketone. | [General Description]
(±)-Hydroxybupropion is a primary metabolite of bupropion. Bupropion is a pharmaceutical used as an antidepressant and a smoking cessation drug sold under the trade names Wellbutrin? and Zyban?. This Certified Spiking Solution? is suitable for use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, urine drug testing, or pharmaceutical research. |
| Safety Data | Back Directory | [Hazard Codes ]
F,Xn | [Risk Statements ]
11-20/21/22-36 | [Safety Statements ]
16-36/37 | [RIDADR ]
UN 1648 3 / PGII | [WGK Germany ]
2 | [HS Code ]
3822900000 | [Storage Class]
3 - Flammable liquids | [Hazard Classifications]
Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Flam. Liq. 2 |
|
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Sigma-Aldrich
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https://www.sigmaaldrich.cn |
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