| Identification | Back Directory | [Name]
Esomeprazole Sodium D6 | [CAS]
922731-04-2 | [Synonyms]
Esomeprazole Sodium D6
[2H6]-Esomeprazole Sodium
Esomeprazole Sodium D6Q: What is
Esomeprazole Sodium D6 Q: What is the CAS Number of
Esomeprazole Sodium D6 Q: What is the storage condition of
Esomeprazole Sodium D6 Q: What are the applications of
Esomeprazole Sodium D6 | [Molecular Formula]
C17H20N3NaO3S | [MOL File]
922731-04-2.mol | [Molecular Weight]
369.41 |
| Hazard Information | Back Directory | [Uses]
Esomeprazole-d6 sodium is the deuterium labeled Esomeprazole. Esomeprazole ((S)-Omeprazole) is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of the H+, K+-ATPase in gastric parietal cells. Esomeprazole has the potential for symptomatic gastroesophageal reflux disease research[1][2][3]. | [References]
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Wayne Goh, et al. Use of proton pump inhibitors as adjunct treatment for triple-negative breast cancers. An introductory study. J Pharm Pharm Sci. 2014;17(3):439-46. DOI:10.18433/j34608
[3] Christina Nelson, et al. Therapeutic Efficacy of Esomeprazole in Cotton Smoke-Induced Lung Injury Model. Front Pharmacol. 2017 Jan 26;8:16. DOI:10.3389/fphar.2017.00016
[4] Thomas J Johnson, et al. Esomeprazole: a clinical review. Am J Health Syst Pharm. 2002 Jul 15;59(14):1333-9. DOI:10.1093/ajhp/59.14.1333 |
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