| Identification | Back Directory | [Name]
GSK962040 | [CAS]
923565-21-3 | [Synonyms]
Camicil
GSK962040
Camicinal
Lopixibat chloride
GSK962040
(Camicinal
1-[4-[(3-Fluorophenyl)amino]-1-piperidinyl]-2-[4-[[(3S)-3-methyl-1-piperazinyl]methyl]phenyl]ethanone
Ethanone, 1-[4-[(3-fluorophenyl)amino]-1-piperidinyl]-2-[4-[[(3S)-3-methyl-1-piperazinyl]methyl]phenyl]- | [Molecular Formula]
C25H33FN4O | [MOL File]
923565-21-3.mol | [Molecular Weight]
424.55 |
| Chemical Properties | Back Directory | [Melting point ]
144℃ | [Boiling point ]
610.0±55.0 °C(Predicted) | [density ]
1.175±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
9.21±0.40(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Definition]
ChEBI:Camicinal is a member of acetamides. | [Biological Activity]
Camicinal (GSK962040) is a motilin receptor agonist with a pEC50 of 7.9. | [in vivo]
Camicinal (GSK962040) (5 mg free base kg 1) also produced an increase in total faecal weight over the 2-h postdose period (21.2 ± 4.5 g; P < 0.05). It induced phasic contractions, the duration of which was dose-related (48 and 173 min for 3 and 6 mg kg 1), driven by mean plasma concentrations >1.14 μmol L 1. After the effects of GSK962040 faded, migrating motor complex (MMC) activity returned. | [target]
pEC50: 7.9 (Motilin Receptor). | [storage]
Store at -20°C |
|
| Company Name: |
SPIRO PHARMA
|
| Tel: |
|
| Website: |
www.spiropharma.com.cn |
| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
| Company Name: |
ChemeGen 中国
|
| Tel: |
18818260767 |
| Website: |
https://www.chemegen.com |
| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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