| Identification | Back Directory | [Name]
Methyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate | [CAS]
923942-34-1 | [Synonyms]
Febuxostat-54
Febuxostat Methyl Ester Impurity
Methyl 2-(3-cyano-4-isobutoxyphenyl)-4-Methylthiazole-5-carboxylate
Methyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate
2-(3-(ethoxycarbonyl)-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid
Methyl 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methylthiazole-5-carboxylate
5-Thiazolecarboxylic acid, 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-, methyl ester
Febuxostat Impurity 8/Febuxostat Methyl Ester/Methyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate | [Molecular Formula]
C17H18N2O3S | [MDL Number]
MFCD20488021 | [MOL File]
923942-34-1.mol | [Molecular Weight]
330.4 |
| Chemical Properties | Back Directory | [Melting point ]
157-159°C | [Boiling point ]
486.8±55.0 °C(Predicted) | [density ]
1.24 | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
0.95±0.10(Predicted) | [color ]
White |
| Hazard Information | Back Directory | [Uses]
Methyl 2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methylthiazole-5-carboxylate is a 4-Methylthiazole-5-carboxylic Acid derivative as a potential inhibitor of mucin onco proteins for breast cancer therapy.Also, it is derived from Febuxostat (F229000), which is a xanthine oxidase/xanthine dehydrogenase inhibitor and used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout. |
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