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924855-67-4

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924855-67-4 Structure

924855-67-4 Structure
IdentificationBack Directory
[Name]

N-{4-[(4-methylbenzyl)oxy]benzyl}-N-(4-piperidinylmethyl)amine
[CAS]

924855-67-4
[Synonyms]

DCSM06
N-{4-[(4-methylbenzyl)oxy]benzyl}-N-(4-piperidinylmethyl)amine
1-{4-[(4-methylbenzyl)oxy]phenyl}-N-(piperidin-4-ylmethyl)methanamine
4-Piperidinemethanamine, N-[[4-[(4-methylphenyl)methoxy]phenyl]methyl]-
[Molecular Formula]

C21H28N2O
[MOL File]

924855-67-4.mol
[Molecular Weight]

324.46
Chemical PropertiesBack Directory
[Boiling point ]

473.0±30.0 °C(Predicted)
[density ]

1.044±0.06 g/cm3(Predicted)
[pka]

10.54±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

DCSM06 is an inhibitor for the bromodomain of SWI/SNF chromatin remodeling complexe SMARCA2 with an IC50 of 9.7 μM[1]
[References]

[1] Lu T, et al., Identification of small molecule inhibitors targeting the SMARCA2 bromodomain from a high-throughput screening assay. Acta Pharmacol Sin. 2018 Sep;39(9):1544-1552. DOI:10.1038/aps.2017.188
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