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927827-98-3

927827-98-3 Structure

927827-98-3 Structure
IdentificationBack Directory
[Name]

MMP INHIBITOR III
[CAS]

927827-98-3
[Synonyms]

MMP INHIBITOR III
Butanediamide, N4-hydroxy-N1-[1-[(methylamino)carbonyl]-3-phenylpropyl]-2-(2-methylpropyl)-
[Molecular Formula]

C19H29N3O4
[MDL Number]

MFCD03457527
[MOL File]

927827-98-3.mol
[Molecular Weight]

363.45
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

DMSO: 5mg/mL
[form ]

lyophilized solid
[color ]

off-white
Safety DataBack Directory
[WGK Germany ]

WGK 1
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

A homophenylalanine-hydroxamic acid based broad-spectrum cell-permeable, reversible inhibitor of matrix metalloproteinases (supplied as a racemic mixture). Inhibits MMP-1 (IC50 = 7.4 nM), MMP-2 (IC50 = 2.3 nM), MMP-3 (IC50 = 135 nM), MMP-7 (IC50 = 10-100 nM), and MMP-13 (IC50 = 1-10 nM).
[Biological Activity]

Cell permeable: yes''Primary Target
MMP-1''Product does not compete with ATP.''Reversible: yes''Target IC50: 7.4 nM2.3 nM135 nM10-100 nM1-10 nMagainst MMP-1MMP-2MMP-3MMP-7and MMP-13respectively
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