| Identification | Back Directory | [Name]
PEG22 | [CAS]
928211-42-1 | [Synonyms]
PEG22
PEG21
HO-PEG21-OH
PEG (n=21) (polyethylene glycol 1000) | [Molecular Formula]
C42H86O22 | [MDL Number]
MFCD29079392 | [MOL File]
928211-42-1.mol | [Molecular Weight]
943.12 |
| Chemical Properties | Back Directory | [Boiling point ]
838.8±60.0 °C(Predicted) | [density ]
1.117±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
14.06±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
PEG22 is a polymeric structure consisting of ethylene glycol units and two terminal hydroxyl groups. The hydroxyl group can react to further derivatize the compound. The hydrophilic PEG linkers increase the water solubility of the compound in aqueous media. The water solubility properties of the PEG linker are enhanced with longer PEG chains. | [Uses]
HO-PEG21-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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