| Identification | Back Directory | [Name]
Dithieno[2,3-d:2',3'-d']pyrazino[1,2-a:4,5-a']dipyrimidine-4,11(6H,13H)-dione, 3,10-di-2-furanyl- | [CAS]
930455-91-7 | [Synonyms]
Dithieno[2,3-d:2',3'-d']pyrazino[1,2-a:4,5-a']dipyrimidine-4,11(6H,13H)-dione, 3,10-di-2-furanyl- | [Molecular Formula]
C22H12N4O4S2 | [MOL File]
930455-91-7.mol | [Molecular Weight]
460.49 |
| Chemical Properties | Back Directory | [Boiling point ]
687.7±65.0 °C(Predicted) | [density ]
1.81±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
-1.11±0.20(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
RGB-1 is a polycyclic aromatic hydrocarbon molecule and a stabilizer of RNA G-quadruplexes. RGB-1 can promote the inhibition of RNA translation and reduce the expression of NRAS proto-oncogene in breast cancer cells[1]. | [References]
[1] Katsuda Y, et al. A Small Molecule That Represses Translation of G-Quadruplex-Containing mRNA. J Am Chem Soc. 2016 Jul 27;138(29):9037-40. DOI:10.1021/jacs.6b04506 |
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