| Identification | Back Directory | [Name]
1-ETHYNYLCYCLOHEXENE | [CAS]
931-49-7 | [Synonyms]
TIMTEC-BB SBB002648
1-ETHYNYLCYCLOHEXENE
1-ethvnvlcvclohexene
1-ethynyl-cyclohexen
Cyclohexene, 1-ethynyl-
1-ETHYNYL-1-CYCLOHEXENE
1-Cyclohexenylacetylene
1-ethynylcyclohex-1-ene
1-(1-Cyclohexenyl)ethyne
(1-Cyclohexenyl)acetylene
1-(1-Cyclohexenyl)acetylene
1-(1-ETHYNYL)-1-CYCLOHEXENE
1-ETHYNYLCYCLOHEXENE ISO 9001：2015 REACH
Cyclohexene, 1-ethynyl- (6CI, 7CI, 8CI, 9CI) | [Molecular Formula]
C8H10 | [MDL Number]
MFCD00001568 | [MOL File]
931-49-7.mol | [Molecular Weight]
106.17 |
| Chemical Properties | Back Directory | [Boiling point ]
148-151 °C(lit.)
| [density ]
0.903 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.496(lit.)
| [Fp ]
85 °F
| [storage temp. ]
2-8°C | [form ]
clear liquid | [color ]
Colorless to Light orange to Yellow | [λmax]
224nm(EtOH)(lit.) | [InChI]
1S/C8H10/c1-2-8-6-4-3-5-7-8/h1,6H,3-5,7H2 | [InChIKey]
DKFHWNGVMWFBJE-UHFFFAOYSA-N | [SMILES]
C#CC1=CCCCC1 | [EPA Substance Registry System]
Cyclohexene, 1-ethynyl- (931-49-7) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
10-36/37/38 | [Safety Statements ]
16-26-36/37/39 | [RIDADR ]
UN 3295 3/PG 3
| [WGK Germany ]
3
| [HazardClass ]
3.2 | [PackingGroup ]
III | [HS Code ]
2902110000 | [Storage Class]
3 - Flammable liquids | [Hazard Classifications]
Eye Irrit. 2
Flam. Liq. 3
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Uses]
1-ETHYNYLCYCLOHEXENE can be used to prepare 4-phenoxyquinoline-N-sulfonylamidine compounds with the following structure. These compounds can act as tyrosine kinase inhibitors, especially c-Met inhibitors. c-Met is highly expressed in most solid tumors and some sarcomas and is closely associated with poor prognosis, such as lung cancer, breast cancer, colon cancer, prostate cancer, liver cancer, gastric cancer, and glioma. Furthermore, patients with high HGF/c-Met expression levels have stronger resistance to chemotherapy and radiotherapy. Besides abnormal HGF/c-Met expression, c-Met can also be activated in cancer patients through gene mutation and gene amplification. | [Synthesis Reference(s)]
Synthetic Communications, 16, p. 283, 1986 DOI: 10.1080/00397918608076310 |
|
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Infinity SCI
|
| Telephone: |
400-106-2016 17800804092 |
| Website: |
http://www.infsci.com |
|