| Identification | Back Directory | [Name]
4-(2-Furanyl)-4,10-dihydro-2-methylpyrimido[1,2-a]benzimidazole-3-carboxylic acid-1-methylethyl ester | [CAS]
932191-62-3 | [Synonyms]
ISAM 140
4-(2-Furanyl)-4,10-dihydro-2-methylpyrimido[1,2-a]benzimidazole-3-carboxylic acid-1-methylethyl ester
Pyrimido[1,2-a]benzimidazole-3-carboxylic acid, 4-(2-furanyl)-4,10-dihydro-2-methyl-, 1-methylethyl ester | [Molecular Formula]
C19H19N3O3 | [MOL File]
932191-62-3.mol | [Molecular Weight]
337.37 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMSO|6.75|20| | [form ]
Solid | [color ]
White to off-white | [InChI]
1S/C19H19N3O3/c1-11(2)25-18(23)16-12(3)20-19-21-13-7-4-5-8-14(13)22(19)17(16)15-9-6-10-24-15/h4-11,17H,1-3H3,(H,20,21) | [InChIKey]
NYHLRBMDXQBOIB-UHFFFAOYSA-N | [SMILES]
CC1=C(C(OC(C)C)=O)C(C2=CC=CO2)N3C(N1)=NC4=C3C=CC=C4 |
| Hazard Information | Back Directory | [Uses]
ISAM 140 is a potent and highly selective A2B Adenosine receptor antagonist. | [Biological Activity]
ISAM-140 is a potent and selective A2B adenosine receptor antagonist (A2BAR). ISAM-140 exhibits remarkable selectivity over A1A2Aand A3 adenosine receptors. | [IC 50]
hA2B: 3.49 nM (Ki) | [storage]
Store at -20°C |
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