| Identification | Back Directory | [Name]
Bromoacetamide-PEG3-propargyl | [CAS]
932741-11-2 | [Synonyms]
Bromoacetamide-PEG3-propargyl
Acetamide, 2-bromo-N-[2-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]ethyl]- | [Molecular Formula]
C11H18BrNO4 | [MDL Number]
MFCD32642009 | [MOL File]
932741-11-2.mol | [Molecular Weight]
308.17 |
| Hazard Information | Back Directory | [Uses]
Bromoacetamide-PEG3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromoacetamide-PEG3-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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