| Identification | Back Directory | [Name]
(+/-)-BAY K 8644 | [CAS]
93468-89-4 | [Synonyms]
(+/-)-BAY K 8644
BAY K-8644 (+/-)
(±)-Bay K 8644 - CAS 93468-89-4 - Calbiochem
(+)-(S)-1,4-dihydro-2,6-dimethyl-3-nitro-4-(2-trifluoromethylphenyl)pyridine-5-carboxylic acid
1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-[TRIFLUOROMETHYL]PHENYL)PYRIDINE-3-CARBOXYLIC ACID METHYL ESTER
1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2'-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID METHYL ESTER
1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID, METHYL ESTER | [Molecular Formula]
C16H15F3N2O4 | [MDL Number]
MFCD00036697 | [MOL File]
93468-89-4.mol | [Molecular Weight]
356.3 |
| Hazard Information | Back Directory | [Definition]
ChEBI: Methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate is a pentasubstituted dihydropyridine carrying methoxycarbonyl, 2-(trifluoromethyl)phenyl and nitro substituents at positions 3, 4 and 5 respectively as well as two methyl substituents at positions 2 and 6. It is a dihydropyridine, a methyl ester, a C-nitro compound and a member of (trifluoromethyl)benzenes. | [General Description]
Synthetic dihydropyridine derivative that acts as an active Ca2+ slow channel agonist in neuroendocrine, muscle, thyroid and other cell types. Prolongs single channel open time without affecting the close time. An L-type Ca2+ channel agonist. Composed of two optical isomers. The (-)-enantiomer has strong vasoconstrictive, positive inotropic, and Ca2+ agonistic properties, whereas the (+)-enantiomer has weakly vasodilating, negative inotropic, and Ca2+ antagonistic properties. The net effect of the racemic mix is that of the negative enantiomer. Promotes β-cell proliferation/regeneration. | [Biochem/physiol Actions]
Primary TargetL-type Ca2+ channel |
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| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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