935262-95-6

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935262-95-6 Structure

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[Name] 2-Oxazolidinone, 3-[1-(1H-indol-2-ylmethyl)-4-piperidinyl]-5-(6-methoxy-4-quinolinyl)-, (5R)-
[CAS] 935262-95-6
[Synonyms] SB-649701 2-Oxazolidinone, 3-[1-(1H-indol-2-ylmethyl)-4-piperidinyl]-5-(6-methoxy-4-quinolinyl)-, (5R)-
[Molecular Formula] C27H28N4O3
[MOL File] 935262-95-6.mol
[Molecular Weight] 456.54

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[Uses] SB-649701 is a potent human CCR8 antagonist, with a pIC50 of 7.7. AZ084 can be used for the research of asthma[1].
[IC 50] CCR8: 7.7 (pIC₅₀)
[References] [1] Jin J, et, al. Oxazolidinones as novel human CCR8 antagonists. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1722-5. DOI:10.1016/j.bmcl.2006.12.076

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