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937051-40-6

937051-40-6 Structure

937051-40-6 Structure
IdentificationBack Directory
[Name]

DF 461
[CAS]

937051-40-6
[Synonyms]

DF 461
4H,6H-[1,2,4]Triazolo[4,3-a][4,1]benzoxazepine-4-acetic acid, 8-chloro-6-(2-chloro-3-methoxyphenyl)-1-(trifluoromethyl)-, (4R,6S)-
[Molecular Formula]

C20H14Cl2F3N3O4
[MOL File]

937051-40-6.mol
[Molecular Weight]

488.24
Hazard InformationBack Directory
[Description]

DF-461 is a squalene synthase inhibitor.
[Uses]

DF 461 is a sterol synthase inhibitor with significant inhibitory activity. DF 461 shows high selectivity for the liver and can effectively inhibit cholesterol synthesis in rat liver. DF 461 has shown the effect of lowering plasma lipids in repeated dosing studies in non-rodents[1].
[References]

[1] Discovery of DF-461, a Potent Squalene Synthase Inhibitor
937051-40-6 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website: www.targetmol.com/
Company Name: SPIRO PHARMA  
Tel:
Website: www.spiropharma.com.cn
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