| Identification | Back Directory | [Name]
N2-(Isopropylphenoxyacetyl)guanosine | [CAS]
937205-20-4 | [Synonyms]
N2-(Isopropylphenoxyacetyl)guanosine
N-(9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-2-(4-isopropylphenoxy)acetamide | [Molecular Formula]
C21H25N5O7 | [MDL Number]
MFCD30718401 | [MOL File]
937205-20-4.mol | [Molecular Weight]
459.45 |
| Hazard Information | Back Directory | [Uses]
N-[2-[4-(1-Methylethyl)phenoxy]acetyl]guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1]. | [References]
[1] Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51. DOI:10.1073/pnas.0631696100 |
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