ChemicalBook--->CAS DataBase List--->94071-26-8

94071-26-8

Request For Quotation
94071-26-8 Structure

94071-26-8 Structure
IdentificationBack Directory
[Name]

CEREBELLIN
[CAS]

94071-26-8
[Synonyms]

CEREBELLIN
SGSAKVAFSAIRSTNH
Cerebellin (rat)
SER-GLY-SER-ALA-LYS-VAL-ALA-PHE-SER-ALA-ILE-ARG-SER-THR-ASN-HIS
H-SER-GLY-SER-ALA-LYS-VAL-ALA-PHE-SER-ALA-ILE-ARG-SER-THR-ASN-HIS-OH
Nh2-Ser-Gly-Ser-Ala-Lys-Val-Ala-Phe-Ser-Ala-Ile-Arg-Ser-Thr-Asn-His-OH
Cerebellin H-Ser-Gly-Ser-Ala-Lys-Val-Ala-Phe-Ser-Ala-Ile-Arg-Ser-Thr-Asn-His-OH
SER-GLY-SER-ALA-LYS-VAL-ALA-PHE-SER-ALA-ILE-ARG-SER-THR-ASN-HIS: SGSAKVAFSAIRSTNH
L-Histidine, L-serylglycyl-L-seryl-L-alanyl-L-lysyl-L-valyl-L-alanyl-L-phenylalanyl-L-seryl-L-alanyl-L-isoleucyl-L-arginyl-L-seryl-L-threonyl-L-asparaginyl-
[Molecular Formula]

C69H113N23O23
[MDL Number]

MFCD00167553
[MOL File]

94071-26-8.mol
[Molecular Weight]

1632.78
Chemical PropertiesBack Directory
[storage temp. ]

-15°C
[form ]

Solid
[color ]

White to off-white
[Sequence]

H-Ser-Gly-Ser-Ala-Lys-Val-Ala-Phe-Ser-Ala-Ile-Arg-Ser-Thr-Asn-His-OH
Hazard InformationBack Directory
[Uses]

Cerebellin is a neuromodulatory peptide widely distributed in the central nervous system.
[in vivo]

Cerebellin potently stimulates norepinephrine release by rat adrenal medulla, acting through adenylate-cyclase/PKA-coupled receptors, and enhances adrenocortical steroid secretion in vivo (i.e. when the integrity of adrenal gland is preserved) through an indirect paracrine mechanism involving the release of medullary catecholamines[1]. Cerebellin reduces plasma insulin levels in rats after 1 and 2 h. Cerebellin decreases insulin secretion from isolated rat pancreatic islets at high (11 mM), but not at low (3.33 mM) glucose concentration. Cerebellin inhibits stimulated insulin secretion from clonal rat insulinoma (INS-1) cells, reduces forskolin-induced production of cAMP and intracellular calcium concentration[2].

[References]

[1] Albertin G, et al. Cerebellin stimulates the secretory activity of the rat adrenal gland: in vitro and in vivo studies. Neuropeptides. 2000 Feb;34(1):7-11. DOI:10.1054/npep.1999.0779
[2] Strowski MZ, et al. Insulinostatic activity of cerebellin--evidence from in vivo and in vitro studies in rats. Regul Pept. 2009 Oct 9;157(1-3):19-24. DOI:10.1016/j.regpep.2009.05.010
94071-26-8 suppliers list
Company Name: GL Biochem (Shanghai) Ltd  
Telephone: 21-61263452 13641803416
Website: http://www.glschina.com/
Company Name: Shanghai Hanhong Scientific Co.,Ltd.  
Telephone: 021-54306202 13764082696
Website: https://www.hanhongsci.com
Company Name: Chemsky (shanghai) International Co.,Ltd  
Telephone: 021-50135380
Website: www.shchemsky.com
Company Name: Cellmano Biotech Limited  
Telephone: 0551-65326643 18156095617
Website: https://www.cellmano.com
Company Name: TargetMol Chemicals Inc.  
Telephone: 021-021-33632979 15002134094
Website: https://www.targetmol.cn/
Company Name: Shanghai Xilong Biochemical Technology Co., Ltd.  
Telephone: 021-52907766-8042
Website: www.chemicalbook.com/ShowSupplierProductsList19329/0_EN.htm
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Telephone: 15026964105
Website: www.shyuanye.com
Company Name: Beijing Solarbio Science & Tecnology Co., Ltd.  
Telephone: 17801761073 18101056239
Website: http://www.solarbio.com
Company Name: Nanjing Leon Biological Technology Co., Ltd.  
Telephone: 025-84523390 -127; 17705183659
Website: http://www.njleonbiotech.com
Company Name: Nanjing Peptide Biotech Ltd.  
Telephone: 025-58361106-805 15951641583
Website: http://www.njpeptide.com
Company Name: Chengdu Youngshe Chemical Co., Ltd.  
Telephone: +86-17380623303
Website: https://shop326109856.taobao.com/
Company Name: Hangzhou Peptidego Biotech Co.,Ltd.  
Telephone: 0571-87213919 15967184799
Website: peptidego.com
Company Name: Cellmano Biotech Limited  
Telephone: 0551-65326643 18156095617
Website: http://www.cellmano.com/
Company Name: career henan chemical co  
Telephone: +86-0371-86658258
Website: www.coreychem.com
Company Name: Nanjing chengqimei Biotechnology Co., Ltd  
Telephone: 19850819832
Website: www.chemicalbook.com/ShowSupplierProductsList398701/0_EN.htm
Company Name: Nanchang Tianzhen Biotechnology Co., Ltd  
Telephone: 13758194781 13173652190
Website: www.tanzhenbio.com
Company Name: Nanjing TGpeptide Biotechnology Co.,Ltd.  
Telephone: 18115476705
Website: http://www.tgpeptide.com/Index.aspx
Company Name: Ontores Biotech  
Telephone: 0571-88760729 18072970094
Website: www.ontoresinc.cn
Tags:94071-26-8 Related Product Information
6028-28-0 2497-02-1