| Identification | Back Directory | [Name]
4H-Pyrrolo[3,2-c]pyridin-4-one, 1-ethyl-1,5,6,7-tetrahydro-2-(4-pyridinyl)- | [CAS]
942425-34-5 | [Synonyms]
4H-Pyrrolo[3,2-c]pyridin-4-one, 1-ethyl-1,5,6,7-tetrahydro-2-(4-pyridinyl)- | [Molecular Formula]
C14H15N3O | [MOL File]
942425-34-5.mol | [Molecular Weight]
241.29 |
| Chemical Properties | Back Directory | [Boiling point ]
539.2±50.0 °C(Predicted) | [density ]
1.27±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
15.37±0.20(Predicted) | [color ]
Light yellow to light brown |
| Hazard Information | Back Directory | [Uses]
PKN1/2-IN-1 is a potent, cell penetrant and selective PKN2 (PRK2) inhibitor (IC50=16 nM; Ki=8 nM)[1]. | [Biological Activity]
PKN1/2-IN-1 is a potent, cell penetrant and selective PKN2 (PRK2) inhibitor (IC50=16 nM; Ki=8 nM)[1]. | [storage]
Store at -20°C | [References]
[1]. Scott F, et al. Development of dihydropyrrolopyridinone-based PKN2/PRK2 chemical tools to enable drug discovery. Bioorg Med Chem Lett. 2022;60:128588. |
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