| Identification | Back Directory | [Name]
3-CinnolinecarboxaMide, 4-aMino-8-(2,5-diMethoxyphenyl)-N-propyl- | [CAS]
942436-93-3 | [Synonyms]
AZD-6280
AZD6280
(AZD 6280)
4-amino-8-(2,5-dimethoxyphenyl)-N-propylcinnoline-3-carboxamide
3-CinnolinecarboxaMide, 4-aMino-8-(2,5-diMethoxyphenyl)-N-propyl-
γ-Aminobutyric acid Receptor,GABA Receptor,inhibit,Gamma-aminobutyric acid Receptor,AZD6280,AZD 6280,AZD-6280,Inhibitor | [Molecular Formula]
C20H22N4O3 | [MDL Number]
MFCD21337368 | [MOL File]
942436-93-3.mol | [Molecular Weight]
366.41 |
| Chemical Properties | Back Directory | [density ]
1.225±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 62.5 mg/mL (170.57 mM) | [form ]
Solid | [pka]
11.76±0.46(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
AZD-6280 is a selective GABAA(α2/3) receptor modulator, used for treatment of generalized anxiety disorder. | [storage]
Store at -20°C | [References]
[1] Te Beek ET, et al. The effects of the nonselective benzodiazepine lorazepam and the α2 /α3 subunit-selective GABAA receptor modulators AZD7325 and AZD6280 on plasma prolactin levels. Clin Pharmacol Drug Dev. 2015 Mar;4(2):149-54. doi: 10.1002/cpdd.134. Epub 2014 Aug 28. DOI:10.1002/cpdd.134 |
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BOC Sciences
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1-631-485-4226; 16314854226 |
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https://www.bocsci.com |
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