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942936-75-6

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942936-75-6 Structure

942936-75-6 Structure
IdentificationBack Directory
[Name]

Phen-DC3
[CAS]

942936-75-6
[Synonyms]

Phen-DC3
Phen-DC 3
PHEN-DC-3;PHEN-DC3
2-N,9-N-bis(1-methylquinolin-1-ium-3-yl)-1,10-phenanthroline-2,9-dicarboxamide
[Molecular Formula]

C34H26N6O2+2
[MDL Number]

MFCD31657446
[MOL File]

942936-75-6.mol
[Molecular Weight]

550.62
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : ≥ 34 mg/mL (61.75 mM)
Hazard InformationBack Directory
[Uses]

Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases with IC50s of 65±6 and 50±10 nM, respectively.
[storage]

Store at -20°C
[References]

[1] Bharti SK, et al. Specialization among iron-sulfur cluster helicases to resolve G-quadruplex DNA structures that threaten genomic stability. J Biol Chem. 2013 Sep 27; 288(39):28217-29.
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