| Identification | Back Directory | [Name]
Lanosta-8,20(22)-dien-26-oic acid, 12-(acetyloxy)-3,7-dihydroxy-11,15,23-trioxo-, (3β,7β,12β,20E)- | [CAS]
942950-94-9 | [Synonyms]
Ganoderenic acid K
Lanosta-8,20(22)-dien-26-oic acid, 12-(acetyloxy)-3,7-dihydroxy-11,15,23-trioxo-, (3β,7β,12β,20E)- | [Molecular Formula]
C32H44O9 | [MOL File]
942950-94-9.mol | [Molecular Weight]
572.7 |
| Hazard Information | Back Directory | [Uses]
Ganoderenic acid K is a natural product, that can be isolated from fruiting bodies of Ganoderma lucidum. Ganoderenic acid K shows strong inhibitory activity against HMG-CoA reductase (HMGCR) with IC50 of 16.5 μM[1]. | [References]
[1] Chen B, et al. Triterpenes and meroterpenes from Ganoderma lucidum with inhibitory activity against HMGs reductase, aldose reductase and α-glucosidase. Fitoterapia. 2017 Jul;120:6-16. DOI:10.1016/j.fitote.2017.05.005 |
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