| Identification | Back Directory | [Name]
2H-1-Benzopyran-3-carboxamide, N-[4-(4-ethyl-1-piperazinyl)phenyl]-2-oxo- | [CAS]
943083-58-7 | [Synonyms]
WIC1
2H-1-Benzopyran-3-carboxamide, N-[4-(4-ethyl-1-piperazinyl)phenyl]-2-oxo- | [Molecular Formula]
C22H23N3O3 | [MOL File]
943083-58-7.mol | [Molecular Weight]
377.44 |
| Chemical Properties | Back Directory | [Boiling point ]
636.4±55.0 °C(Predicted) | [density ]
1.281±0.06 g/cm3(Predicted) | [storage temp. ]
-10 to -25°C | [solubility ]
Soluble to 2 mM in DMSO with gentle warming | [form ]
Solid | [pka]
12.15±0.70(Predicted) | [color ]
Yellow to orange |
| Hazard Information | Back Directory | [Description]
WIC1 is a novel potent Wnt inhibitor, promoting airway basal stem cell homeostasis, acting to repress phosphorylation of β-cateninY489 and Tp63 expression. | [Uses]
WIC1 is a potent Wnt inhibitor. WIC1 can be used for the research of cancer[1]. | [storage]
Store at -20°C | [References]
[1] Brigitte N, et al. Compositions and methods for treating cancer and improving epithelial homeostasis. Patent. WO2021133460A1. |
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| Company Name: |
R&D Systems, Inc
|
| Tel: |
18003437475 18003437475 |
| Website: |
www.rndsystems.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|