ChemicalBook--->CAS DataBase List--->943757-71-9

943757-71-9

943757-71-9 Structure

943757-71-9 Structure
IdentificationBack Directory
[Name]

Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-
[CAS]

943757-71-9
[Synonyms]

(R)-Hayashi-Jorgensen Catalyst
R-Diphenylprolinol trimethyl silyl ether
α,α-Diphenyl-D-prolinol Trimethylsilyl Ether
(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
(R)-Diphenylprolinol Trimethyl Silyl Ether,99%e.e.
alpha,alpha-Diphenyl-D-prolinol Trimethylsilyl Ether
(R)-2-[Diphenyl(trimethylsilanyloxy)methyl]pyrrolidine
(2R)-2-[Diphenyl[(trimethylsilyl)oxy]methyl]pyrrolidine
[diphenyl-[(2R)-pyrrolidin-2-yl]methoxy]-trimethylsilane
(R)-Diphenylprolinol trimethyl silyl ether, 95% (99% ee)
Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-
(R)-(+)-a,a-Diphenyl-2-pyrrolidineMethanol TriMethylsilyl Ether
(R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether
(R)-(+)-α,α-Diphenyl-2-pyrrolidineMethanol triMethylsilyl ether 96%
(R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol Trimethylsilyl Ether
(R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidineMethanol triMethylsilyl ether 96%
(R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether solution
[Molecular Formula]

C20H27NOSi
[MDL Number]

MFCD09265100
[MOL File]

943757-71-9.mol
[Molecular Weight]

325.525
Chemical PropertiesBack Directory
[Boiling point ]

412.7±35.0 °C(Predicted)
[density ]

1.021
[refractive index ]

n20/D1.5509
[Fp ]

>110℃
[storage temp. ]

2-8°C
[form ]

clear liquid
[pka]

10.01±0.10(Predicted)
[color ]

Light orange to Yellow to Green
[Optical Rotation]

[α]22/D +52±5°, c = 1 in chloroform
[InChI]

InChI=1S/C20H27NOSi/c1-23(2,3)22-20(19-15-10-16-21-19,17-11-6-4-7-12-17)18-13-8-5-9-14-18/h4-9,11-14,19,21H,10,15-16H2,1-3H3/t19-/m1/s1
[InChIKey]

RSUHWMSTWSSNOW-LJQANCHMSA-N
[SMILES]

N1CCC[C@@H]1C(C1=CC=CC=C1)(C1=CC=CC=C1)O[Si](C)(C)C
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P264-P271-P280-P302+P352-P305+P351+P338
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26
[WGK Germany ]

3
[HS Code ]

2933.99.8290
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Hazard InformationBack Directory
[Uses]

(R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether can be used as a catalyst to synthesize:
  • Glycofused tricyclic derivatives, which are used in the development of amyloid β-peptide diagnostic tools.
  • Cyclohexene carbaldehyde derivatives by reacting benzoylnitromethane with aliphatic enals.

[General Description]

(R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether is a diarylprolinol silyl ether organocatalyst.
Spectrum DetailBack Directory
[Spectrum Detail]

Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-(943757-71-9)1HNMR
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