| Identification | Back Directory | [Name]
N-{4-[(anilinocarbonyl)amino]phenyl}benzamide | [CAS]
945114-10-3 | [Synonyms]
Sirtuin-1 inhibitor 1
N-{4-[(anilinocarbonyl)amino]phenyl}benzamide
Benzamide, N-[4-[[(phenylamino)carbonyl]amino]phenyl]- | [Molecular Formula]
C20H17N3O2 | [MOL File]
945114-10-3.mol | [Molecular Weight]
331.37 |
| Chemical Properties | Back Directory | [Boiling point ]
376.0±25.0 °C(Predicted) | [density ]
1.332±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
13.26±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Sirtuin-1 inhibitor 1 (Compound 8) is an inhibitor of Sirtuin-1 that plays important roles in obesity-induced diabetes and aging-related diseases[1]. | [IC 50]
SIRT1 | [References]
[1] Anastasiia Gryniukova, et al. AI-Powered Virtual Screening of Large Compound Libraries Leads to the Discovery of Novel Inhibitors of Sirtuin-1. J Med Chem. 2023 Aug 10;66(15):10241-10251. DOI:10.1021/acs.jmedchem.3c00128 |
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Aronis
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+79265780336 |
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www.aronis.ru |
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