| Identification | Back Directory | [Name]
TG53 | [CAS]
946369-04-6 | [Synonyms]
TG53
5-chloro-N-[4-[[4-(dimethylamino)-6-methylpyrimidin-2-yl]amino]phenyl]-2-methoxybenzamide
Benzamide, 5-chloro-N-[4-[[4-(dimethylamino)-6-methyl-2-pyrimidinyl]amino]phenyl]-2-methoxy- | [Molecular Formula]
C21H22ClN5O2 | [MDL Number]
MFCD09238426 | [MOL File]
946369-04-6.mol | [Molecular Weight]
411.88 |
| Chemical Properties | Back Directory | [density ]
1.324±0.06 g/cm3(Predicted) | [solubility ]
DMSO: Soluble: =10 mg/ml
Ethanol: Slightly soluble: 0.1-1 mg/ml | [pka]
12?+-.0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
TG53 is a novel inhibitor of tissue transglutaminase (TG2) and fibronectin (FN) protein-protein interaction. | [References]
[1] BAKHTIYOR YAKUBOV. Small molecule inhibitors target the tissue transglutaminase and fibronectin interaction.[J]. PLoS ONE, 2014: e89285. DOI: 10.1371/journal.pone.0089285 |
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