| Identification | Back Directory | [Name]
Ascaroside C6 | [CAS]
946524-24-9 | [Synonyms]
Ascaroside C6
2-Hexanone, 5-[(3,6-dideoxy-α-L-arabino-hexopyranosyl)oxy]-, (5R)- | [Molecular Formula]
C12H22O5 | [MDL Number]
MFCD32197414 | [MOL File]
946524-24-9.mol | [Molecular Weight]
246.3 |
| Chemical Properties | Back Directory | [Boiling point ]
411.9±45.0 °C(Predicted) | [density ]
1.14±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Liquid | [pka]
13.55±0.70(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Uses]
Ascr#2 is an ascaroside isolated from Caenorhabditis elegans, potently promotes dauer formation, and also acts as a potent male attractant combined with ascr#3 at low concentration[1]. | [Definition]
ChEBI: Ascr#2 is a hydroxy ketone ascaroside obtained by formal condensation of the hydroxy group of (5R)-5-hydroxyhexan-2-one with ascarylopyranose (the alpha anomer). It is a major component of the dauer pheromone, used by the nematode Caenorhabditis elegans as a population-density signal to promote entry into an alternate larval stage, the nonfeeding and highly persistent dauer diapause, and also synergises with ascr#3, ascr#4, and ascr#8 in male attraction. It has a role as a Caenorhabditis elegans metabolite and a pheromone. It is a methyl ketone and a hydroxy ketone ascaroside. It is functionally related to a (5R)-5-hydroxyhexan-2-one. | [References]
[1] Srinivasan J, et al. A blend of small molecules regulates both mating and development in Caenorhabditis elegans. Nature. 2008 Aug 28;454(7208):1115-8. DOI:10.1038/nature07168 |
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