| Identification | Back Directory | [Name]
Sornidipine | [CAS]
95105-77-4 | [Synonyms]
Sornidipine
D-Glucitol, 1,4:3,6-dianhydro-, 5-[5-methyl (4R)-1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate]
5-O-[(3S,3aR,6R,6aR)-3-hydroxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] 3-O-methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate | [Molecular Formula]
C22H24N2O9 | [MDL Number]
MFCD00869137 | [MOL File]
95105-77-4.mol | [Molecular Weight]
460.43 |
| Chemical Properties | Back Directory | [Boiling point ]
641.039±55.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.446±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [pka]
13.249±0.40(predicted) |
| Hazard Information | Back Directory | [Uses]
Sornidipine is a calcium channel blocker. Sornidipine also reduces neurogenic inflammation. Sornidipine reduces the inflow of calcium ions into cells by blocking L-type calcium channels, thereby reducing the contraction of vascular smooth muscle, leading to vasodilation and decreased blood pressure. Sornidipine can be used to study the cardiovascular system especially in hypertension and related cardiovascular diseases[1]. | [References]
[1] Clifford J, et al. Permanently charged sodium and calcium channel blockers as anti-inflammatory agents.WO2011006073A1.2021-06-02 |
|
|