| Identification | Back Directory | [Name]
TRx0237 (LMTX) | [CAS]
951131-15-0 | [Synonyms]
E79ZM68IOZ
TRX-0237 HBr
TRx0237 (LMTX)
Hydromethylthionine HBr
Hydromethylthionine HBr(TRX0237)
Leucomethylene Blue dihydrobromide
3-N,3-N,7-N,7-N-tetramethyl-10H-phenothiazine-3,7-diamine | [EINECS(EC#)]
692-122-1 | [Molecular Formula]
C16H20BrN3S | [MDL Number]
MFCD28556898 | [MOL File]
951131-15-0.mol | [Molecular Weight]
366.32 |
| Hazard Information | Back Directory | [Uses]
Hydromethylthionine dihydrobromide (Leukomethylene blue dihydrobromide) is a potent inhibitor of TAU protein aggregation. Hydromethylthionine dihydrobromide reduces neurodegeneration by interacting with TAU proteins and preventing them from forming neurotoxic aggregates. Hydromethylthionine dihydrobromide can be used in the study of Alzheimer's disease and other TAU related disorders[1]. | [References]
[1] Kondak C, et al. Hydromethylthionine enhancement of central cholinergic signalling is blocked by rivastigmine and memantine[J]. Journal of neurochemistry, 2022, 160(2): 172-184. DOI:10.1111/jnc.15553 |
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