| Identification | Back Directory | [Name]
Pyrimido[4,5-b]quinoline-3(4H)-acetamide, 6,7,8,9-tetrahydro-N-(6-methoxy-2-benzothiazolyl)-4-oxo- | [CAS]
951588-85-5 | [Synonyms]
SARS-CoV-2 nsp13-IN-6
Pyrimido[4,5-b]quinoline-3(4H)-acetamide, 6,7,8,9-tetrahydro-N-(6-methoxy-2-benzothiazolyl)-4-oxo- | [Molecular Formula]
C21H19N5O3S | [MOL File]
951588-85-5.mol | [Molecular Weight]
421.47 |
| Hazard Information | Back Directory | [Uses]
SARS-CoV-2 nsp13-IN-6 (compound C5) is a potent SARS-CoV-2 non-structural protein 13 (nsp13) inhibitor with IC50 values of 27 and 33 μM for ssDNA+ ATPase and ssDNA- ATPase. SARS-CoV-2 nsp13-IN-6 can be used for researching anti-COVID-19[1]. | [References]
[1] Yazdi AK, et al. Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors. ACS Infect Dis. 2022 Jul 13. DOI:10.1021/acsinfecdis.2c00165 |
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