| Identification | Back Directory | [Name]
N-[2-(1H-indol-3-yl)ethyl]-N'-[2-[2-(1H-indol-3-yl)ethylcarbamoyl]phenyl]oxamide | [CAS]
951948-78-0 | [Synonyms]
VS-15
N-[2-(1H-indol-3-yl)ethyl]-N'-[2-[2-(1H-indol-3-yl)ethylcarbamoyl]phenyl]oxamide
Ethanediamide, N1-[2-(1H-indol-3-yl)ethyl]-N2-[2-[[[2-(1H-indol-3-yl)ethyl]amino]carbonyl]phenyl]- | [Molecular Formula]
C29H27N5O3 | [MOL File]
951948-78-0.mol | [Molecular Weight]
493.56 |
| Hazard Information | Back Directory | [Uses]
VS-15, a IDO1 inhibitor, selectively binds the heme-free form of IDO1. VS-15 is described as an iNOS inhibitor based on the reduction of NO production[1]. | [References]
[1] Eleonora Panfili, et al. Identification of a Compound Inhibiting Both the Enzymatic and Nonenzymatic Functions of Indoleamine 2,3-Dioxygenase 1. ACS Pharmacol Transl Sci. 2024 Sep 12;7(10):3056-3070. DOI:10.1021/acsptsci.4c00265 |
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